Overall Responsibility:
We work in a highly collaborative environment as a team of biologists, chemists, computational scientists, and engineers. We seek an experienced bioinformatics scientist to partner with the newly formed Therapeutics Development and Translational Science (TD/TS) Platform within the Broad Institute to provide rigorous data-analysis collaborative support for TD/TS project teams. The primary role is to enable TD/TS projects to leverage modern and next-generation algorithms, data visualizations, and user interfaces to integrate a diverse set of data types. The successful candidate will develop analysis methods and tools, perform basic research, and develop and maintain data-analysis pipelines to support multiple projects. The candidate will serve as a primary analyst on TD/TS projects, including method development and biological interpretation, and will co-author research papers with the Director, group members, and collaborators. The candidate should be expert at handling and ana
lysis of high-throughput datasets, and integrating data from multiple diverse sources, bringing critical organizational, time-management, and data-management skills to the position.
Characteristic Duties:
* Organizes analysis project plans, determining and executing computational methods
* Conceives, implements, and tests statistical models; works with wet-lab researchers to translate these models into testable experiments
* Analyzes data from experiments; presents data and experimental results to collaborating scientists
* Independently develops methods, organizing workflows, and coordinating other researchers toward rapid analysis prototypes
* Develops data-analysis strategies, writes algorithms, and deploys computational tools for the exploration of high-dimensional datasets
* Explores novel data representation modes with an emphasis on integrating diverse data types
* Serves as a primary point of contact between the Computational Chemical Biology Research Group and the TD/TS Platform
* Performs complex analysis and experiments to evaluate and troubleshoot new datasets
* Interacts with bench scientists to complete analyses and interpretations, prepares materials for reports and presentations, and presents results at review meetings and scientific conferences.
* Works independently and collaboratively toward successful publication of results
* Researches, assesses, and standardizes processes for analysis tools and software
* Proposes and implements upgrades to existing processes to enhance analysis result quality
REQUIREMENTS:
* Ph.D. in mathematical, physical, or computer science or an advanced degree in chemistry or biology
* Bioinformatics Scientist I - 1-3 years of experience involving computational analysis and visualization
* Bioinformatics Scientist II - 4+ years of experience involving computational analysis and visualization.
* Ability to integrate different specialties (cheminformatics, high-throughput screening, gene expression arrays, systems biology) is paramount; prior experience with more than one of these is strongly preferred
* Ability to translate high-level data-processing and -analysis directions into concrete tasks and execute
* Experience with scientific computing software (MATLAB, R, etc.) required
* Experience implementing custom computational tools and software for bioinformatics or cheminformatics required
* Familiarity with domain-specific software tools (Pipeline Pilot, GeneData, GenePattern, etc.) strongly preferred
* Must possess strong organizational skills and an affinity for problem solving
* Excellent written and verbal communications skills, and the ability to work both independently and collaboratively are strongly preferred
* Must possess ability to manage multiple simultaneous long-term computational projects while meeting frequent project deadlines
LOCALE:
Cambridge, MA
HOW TO APPLY:
To apply, please go to: http://www.broadinstitute.org/careers/career-center
